Picricum acidum

Last modified on August 16th, 2018

Picricum Acidum homeopathy medicine – drug proving symptoms from Encyclopedia of Pure Materia Medica by TF Allen, published in 1874. It has contributions from R Hughes, C Hering, C Dunham, and A Lippe.


Picric acid (Carbazotic acid), a trinitrophenol. Formula, C6H3 (NO2)3. OH.

Preparation: Solutions in alcohol (or triturations).


While enjoying the society of gentlemen, the idea of marriage seemed unendurable. Low spirits (second and twelfth days). A great desire to be alone (eleventh day). Very irritable (after third dose, thirteenth day). Great indifference and lassitude (fourth day). Great indifference; lack of will-power to undertake anything (fourth day). Disinclination for mental or physical work; desire to sit still; aversion to talking or movement, with the headache (second day); dulness and indifference; disinclination to talk and study; takes no interest in surrounding things (third day). Can’t collect thoughts at all or study (fifth day). During the day could not keep my thoughts to study; I could read for a little time, then my mind would seem to be played out (sixth day). Prostration of mind after writing for a time (eighth day).


Vertigo. At 6 P.M. vertigo, with nausea, on least motion; at 9 P.M. vertigo and nausea, with the intense pain in frontal region and vertex; could not sit up; greatly aggravated by even raising the head (second day). Vertigo worse, in the evening (thirteenth day). Vertigo, on stooping or bending of the head and on lying down (eleventh day). Dizziness and vertigo, lasting half an hour, worse when rising up from sitting position, at 12 M. (thirteenth day). General Head. Head felt congested (eleventh day). Sensation of fullness and heaviness of the head, with disinclination for mental or physical work, at 12 noon; fullness and heaviness increased until 2 P.M., when it developed into a severe throbbing headache; worse on the left side, but chiefly in the left eye and occipital region; markedly aggravated by going upstairs, which causes an intense throbbing pain in the eyeball; headache relieved at 4 P.M. (second day); fullness and heaviness of the head, followed by throbbing pain in the eye and occiput (left), but not as marked as before (third day). Heavy (fullness) dull pressing pain in the head, as if full of blood (after nine hours). Fullness and heaviness of the head, with disinclination to do anything (after four hours); headache increases, and finally develops into an intense throbbing pain in left side of the head, chiefly in the eyeball and forehead, and extending backwards to occipital region; better from keeping quiet; worse from motion, and greatly aggravated by going upstairs. Heaviness of the head, alternating with a sensation of emptiness (after half an hour). Head feels heavy (first, second, and third days).

Head feels dull and heavy (after seven hours, twelfth day); (third day). Dull heavy feeling in the head (third day). Head feels as if falling forward (after four hours, fifth day).

Headache of a heavy blinding dizzy character, with great fullness; head feels as if it would burst open; head feels as if too small; pains mostly in the vertex and frontal regions; stooping aggravated the pains, and causes vertigo; headache comes on at 9 A.M., and steadily increases until I go to bed; scalp sensitive to touch; sore aching in infraorbital region (after one hour, fifth day). Dull general headache (seventh day). Dull headache; could not get to sleep until 2 o’clock, after going to bed at 9 (tenth day). Dull heavy headache, lasting all day, coming first on the right side, then spreading to the left (ninth day). Slight dull headache (ninth day. A peculiar dull continuous pain all over the head; aggravated by motion, turning the head, and stooping; relieved by lateral pressure upon the head (after seven hours and a half, fourth day). Dull pain diffused throughout the head (sixth day). Severe headache all day, aggravated on rising, better in open air (eleventh day).

Headache, which he never before had, was one of the most marked symptoms. Head much worse, in the evening; cannot study (sixth day); head somewhat affected, in the evening (seventh day).

Headache, with trembling, afternoon and evening (ninth day); headache, in the evening (tenth day). Headache (after first dose, twelfth day); continued (after third dose, twelfth day).

Headache, with head in the head (after first dose, thirteenth day). Headache slight, in the morning, probably in consequence of oversleeping (thirty-ninth day). Slight headache more or less all day, confined to the upper part of anterior and;middle lobes of brain, also above the eyes; the character of the pain is dull, with an occasional shoot of pain (ninth day). Not much headache in the forenoon; more severe in the afternoon (fourteenth day).

Slight headache for two days after taking the medicine. At 8 P.M.

full pressing sensation in the head, from within outwards, as if the head would fly apart; greatly aggravated by motion and by study (second day). At 9 P.M. severe pressing pain in the head, laterally, from within outwards, with sensation as if the frontal bones would split open; aggravated by turning the head, moving the eyes, or from the least motion (second day). Pains generally about the head, relieved by pressure (after ten hours). Felt well before taking the drug, but in a short time pain came in head, and exact repetition of previous symptoms (eighth day). Do not feel able to study on account of pain in head (third day). All the head pains ceased by bandaging the head tightly (fifth day).

Heavy throbbing pains in the head, extending from behind the ears forward;to the supraorbital notch, and thence downward into the eye, with the great soreness and lameness, especially on left side (fifth day). Burning along the coronal suture (after second dose, twelfth day). Head symptoms continued for several days after discontinuance of drug. Forehead. Dull headache in the front and right side of head, with heat in head and upper part of body (after two hours); in the evening pain in the head, with some thirst and heat, chiefly in the temples, and burning sensation in external ears (first day). At 7 P.M. dull steady frontal headache (with vertigo when rising and when walking), (second day). Dull heavy pain in frontal region, extending to the vertex, worse from motion, at 10 A.M.; at 1 P.M. headache worse, aggravated by the least motion, stooping, bowing the head, or rolling the eyes; at 5 P.M. intense pressing headache, as before (second day). Intense pain in frontal region and vertex, with vertigo and nausea, at 9 P.M. (second day). Dull sleepy pain in the forehead, with sour eructations (lasting an hour), at 3 P.M.

(second day). Dull heavy frontal headache, with great heaviness and weakness in small of back and limbs (fourth day). Slight frontal headache, with sickness at the stomach, as from a weight (third day). Headache confined to front part of head; shoots from outside to center, quite severe, lasting all the evening (twelfth day). In thirty minutes a dull pain in forehead and temples, worse on the right side (first, second, and third days); headache not so severe (sixth day). Slight frontal headache, extending to vertex, of a dull heavy tingling character, all of the evening (second day). Same kind of headache as usual in superior part of anterior lobes of brain (after third dose, third day). Headache in anterior and superior part of head, lasting all the evening (eighth day). Headache confined to back part of anterior and top of middle lobes of brain; pain dull, with an occasional throb (eleventh day). Temples. Beating of temporal arteries (first, second, third, twelfth, and thirteenth days). A disagreeable dull headache, severest over right temple, passing around occiput (after four hours, second day). Dull sleepy pain over left temple (after nine hours, fifth day). Sharp and severe pain in right temple, running to back of head (after twenty minutes); soon after it appeared in left temple, extending to suboccipital region; these pains lasted but a short time (first day). Same pains as yesterday, but more severe in left temple; lasted about an hour (after fifteen minutes, second day). Pain in left temple, sharp and neuralgic in character, disappearing in left and going to right temple; it alternated between the two temples, and was more severe than on the two preceding days (after five minutes, third day). Severe sharp intermitting pain in the left temple (after ten hours, sixth day). Sharp cutting pain in left temple, over a small transverse branch of the temporal artery (second day). The pain of the head have been changeable, alternating between right and left temple, sometimes occurring in center of forehead (third to seventh day). The pain in the temples increased, and also the pain in the forehead; all these pains extends over the eyebrow to the inner angle of right eye (after four hours, seventh day). Slight dull and throbbing pain in right temple (after thirty minutes, first day, and after one hour, second day). Pressing headache between the temples (after second dose, eleventh day); headache increased (after third dose, eleventh day). Vertex. Full heavy feeling in the vertex, at 8 A.M. (second day). Full feeling on top of head (tenth day). Full heavy headache in the vertex, worse when stooping and moving eyes (after four hours and a half, third day). Slight headache in top of head, soon after taking medicine (tenth day); same pain in vertex (eleventh day). The usual headache to-day more severe, in the afternoon (fifteenth day). More headache in the vertex, aggravated by studying and bending the head forward (after second dose, sixteenth day). No headache this morning, but during the night, when I awoke, I had considerable through the upper and back part of head; I have felt this several times during the day (sixteenth day). Headache, throbbing on top of head, aggravated by turning to lie on back, with the nausea (tenth day). Slight twinges of pain on top of head, at 9 P.M. (thirty- ninth day).

About 11 A.M. pain in vertex, with slight fever (second day).

Parietals and Occiput. Felt a slight dart of pain on right side of head, about the middle of the afternoon (fourteenth day).

Headache, mostly in right side, with occasionally a shooting pain through the temples from right to left side (seventh day). Pain in the right side of the head, running behind the ear (after two hours and a quarter). Contracted or squeezed sensation of left hemisphere of brain on going into open air, at 6.30 P.M. (second day). Dull pain in right lower occipital region, beginning at 11.15 A.M. and lasting till 12.30 P.M.; the pain came on gradually and as gradually subsided (third day). Pain in right lower occipital region, at 8 P.M., lasting about an hour, and at the same time a sensation as of a band passing along the right parietal eminence (fourth day). At 9.15 A.M. dull pain in right lower occipital region, which comes and goes at short intervals (fifth day). At 1 P.M. pain in lower right occipital region, coming on at intervals since 11 A.M. (eighth day). A dull pain began in right lower occipital region at 8 A.M. and continued two hours (ninth day); beginning about 4 P.M. and lasting until 10 P.M. (eighteenth day). Dull heavy throbbing and burning pains, commencing in occiput and extending forward to supraorbital foramen, and thence down into the eyes, which throb and feel sore to the touch (after ten hours). Pain in lower right occipital region again comes on, lasting about an hour (fourth day). At 6 P.M. pain in lower right occipital region, as though right side of cerebellum was loose; keeps throbbing; worse on walking; better while sitting quiet; passes off in about an hour (fourth day). In the evening, pain in the right and lower part of occiput (eighth day). Pain in right side and lower part of occiput, coming on about 4 P.M., finally extends upwards over towards the right supraorbital region, continuing about three hours (ninth day). In the afternoon, pain for a few minutes in right and lower side of occiput (tenth day). In the afternoon, pain in right and lower side of occiput (fourteenth day). Pain in lower and right side of occiput, in the evening; did not last more than half an hour (nineteenth day). Heavy pain in occipital region, extending down the neck and spine (after nine hours). Pain in back of head and neck (third day).


Bright yellow color of the sclerotic, skin, and urine (second morning). Eyes to-day markedly yellow, being stained by the acid (seventh day). Yesterday I observed a slight dryness of my eyes, and a slight tingling or smarting, worse by constant use and lamp light. This morning there was some thick acrid matter in the corners of my eyes, worse by constant use and lamp light (ninth day). On waking, and for an hour afterwards, eyes felt as though there were sticks in them; inflammation of eyes has partly subsided (eighteenth day); felt all the evening as though there were sticks in them (twentieth day). Sensation as if sand was in the eyes, with smarting pain and acrid tears (fourth day). Eyes feel dry, as if full of sand (seventh day). Eyes have felt throughout the proving as if dry, and inner surface of lids feel rough (tenth day). Awoke with sharp stinging pains in both eyes, at 7 A.M. (sixth day). Eyes feel sore (tenth day). Eyes feel worse on moving them, or turning them upwards (fifth day).

Gaslight hurts the eyes (after ten hours). Orbit. Pressure over both eyes, worse from studying and motion, better from sitting still (after eleven hours, eleventh day). Pain over right eye in supraorbital region, sharp and vibrating stopping a moment or so, and beginning again (lasted half an hour), (after five hours). Dull pain in the supraorbital region, coming from the occiput (after four hours), worse from movement and stooping (second day). Dull, heavy headache in supraorbital region as before (after six hours, eighth day). Slight pain in supraorbital region and in the back of the neck (after three hours and a half).

Severe aching pain in the left supraorbital notch, at 6 P.M.

(eighth day). Head feels disagreeable and sore, especially the supraorbital region, at 5 P.M. (second day). Dull pain in supraorbital region (sixth day). Supraorbital and frontal headache, more or less all day (thirteenth day). Throbbing over the right eye (after four hours, seventh day). Lids. Lids sore and slightly swollen (third day). Styes, with soreness and swelling of lids (fifth day). Margins of lids very red on waking (thirty-ninth day). Agglutination of eyelids, on waking, in the morning; had to “pick my eyes open” (seventeenth day). Great heaviness of the lids; can’t keep them open (fifth day). Heat in upper eyelids, with increased flow of lachrymal secretion (after second dose, thirteenth day). In the evening, heaviness of eyelids, with a little burning in the eyes (sixteenth day).

Heaviness of the lids (after ten hours). Lachrymation.

Lachrymation (fifth day); (after ten hours). Eyes watery; stinging pain in them (after four hours, fifth day). Conjunctiva.

Conjunctivitis (fifth day). Conjunctiva injected (after ten hours). Conjunctiva greatly inflamed, right eye is the worst; hard work to keep eyes open; makes eyes feel sticky to read; eyes better from washing in cold water and in cold air, worse in warm room (seventeenth day). Ball. Aching pain in the eyeballs, which feel sore; worse by moving them;;better by closing them and keeping quiet (second day). Eyeballs sore to touch, with photophobia (third day). Severe, sharp, shooting pain in center of the eye, extending back to occipital region; pain seemed to follow the course of the optic nerve (third day). Sore, painful sensation in the eyeball; pains in the eyes aggravated by strong light, and by turning the eye; cannot bear to look at a bright light (fifth day). Heavy, pressing, smarting, and burning pain in the eyeball, relieved by pressure (after ten hours). A shooting pain from right eyeball to right side of occiput, lasting but a few seconds (after ten minutes). Pupil. Dilated pupils (fifth and seventh days); (after ten hours); (fifth day). Vision. Sight dim and confused (tenth day). Have to bring objects close to the eyes to see them; seem to be looking through a veil; can see to read clearly only at one point, about five inches from the eyes (after ten hours). While reading, sight is blurred, seemingly caused by winking mucus over the pupils (sixteenth day). Everything seems blurred, as if looking through a fog or a thick veil; can read only with book about five inches from the eyes (fifth and seventh days). Air looks smoky (sixteenth day). Sparks before the eyes (after half an hour). Whirling of objects (after half an hour).


Ears began to burn and look puffy, with a sensation as if worms were crawling on them; these symptoms lasted two hours (after six hours). Burning sensation in external ears, with the headache (first day). Pain behind the right ear, running down right side of neck (after four hours, seventh day). Buzzing and hissing in the ears (after half an hour).


Bleeding of the nose (right nostril), with heat and congestion of the head (after six hours and a half); bleeding of right nostril again (after seven hours and a half, and fourteen hours). Nose filled with mucus; can breathe only through the mouth; relieved by going into open air (third and fourth days). Small furuncle in the left nostril. Stinging pain in right side of nose (after four hours, seventh day). Sensation as if something were pressing greatly on the bridge of the nose (fifth day).


Tingling sensation of lips (after thirty minutes, first day, after one hour, second day). Irregular dull pain in inferior maxillary bone, with beating in molar teeth (after two hours and a quarter).


Saliva white, frothy, and stringy; hangs in long strings to the floor (eighth day). Taste sour; bad taste in mouth (after four hours fifth day). Sour bitter taste in the mouth (third day).

Bitter taste in the mouth (second day). Bitter taste in mouth, with great thirst (twelfth day). Bad taste in mouth of gas (fourth day).


Throat sore, feels rough and scrapy on swallowing, better while eating; feeling of soreness only felt on empty deglutition (eighteenth day). (* Took a dose of Cocculus 30/x to-day, for throat. *) Throat sore, worse on the left side, a rough scrapy sensation on swallowing, better after eating, worse after sleep (seventeenth day). Sore throat; disagreeable sensation back of and above soft palate, at 10 A.M. (second day); still continues with great debility (third day). Throat feels raw, scraped, stiff, and hot, as if burnt; throat red; collection of thick white mucus on tonsils; great difficulty in swallowing, with sensation as if throat would split open (eighth day). Raw feeling in the left side of the throat, extending from behind forward to the submaxillary gland; worse when swallowing (second day).

Rough, raw, scraped sensation in the throat (left side), (second day). A feeling as though a plug were in the throat, while swallowing saliva, also immediately after swallowing (fifth day).

Throat dry and husky (fourth day). Sensation as if something was in lower part of oesophagus (second day).


Appetite. Appetite increased till to-day; have no desire for any kind of food, though I eat as usual, but without relish (eighth day). Very hungry, in the evening, obliged to eat (eighth day).

Appetite poor, disgust for food (eleventh day). No appetite for breakfast; could not eat anything (eighth day). No appetite (third day); (fourth day). No appetite; disgust for food; at non (second day). No appetite; aversion to food (second day). Thirst.

Great thirst, with bitter taste in mouth (twelfth day); thirst continues (thirteenth and fourteenth days). Very great thirst for cold water, which is drank in large quantities without relief (eighth day). Some thirst (eleventh day). Some thirst with the headache (first day). Eructations. Frequent eructations (third day). Sour eructations of gas and ingesta (after eleven hours and a half, third day). Intense raising of wind (tenth day). Bitter eructations after breakfast (second day). Nausea. Awoke at 5 A.M., with a deathlike, faint, nauseated feeling in stomach and abdomen, aggravated on rising and moving around; went back to bed, fell asleep, and on waking a second time, experienced the same sensation as on first waking (eighth day); awoke with the nauseated feeling this morning, but not so had as yesterday morning (ninth day). Nauseated faint feeling at epigastrium most of the time (eleventh day); occasionally throughout the day (twelfth day). Nausea, accompanied by intermittent griping pains in the epigastric region, continuing until night (second day).

Nausea (second day). Nausea followed the dry cough (after three hours and a half). After retiring, nausea, with headache (tenth day). Nausea, on retiring (eighth day). Nausea, with the vertigo (second day). Slight nausea, for an hour or two after taking the drug (eighth day). Sickness at the stomach, as from a weight, with slight frontal headache (third day). Water brash (fourth day). Stomach. Oppressive feeling in epigastric region (first, second, third, and thirteenth days). Disagreeable pressure as of a weight in pit of stomach, desire to belch wind, with no result, seemingly powerless to do so (after two hours and a half, second day). All the morning have felt a faint feeling at epigastrium (thirteenth day). Intermittent griping pains in the epigastric region, continuing until night, accompanied the nausea (second day). A dull pain in cardiac region of stomach, while eating breakfast, at 7 A.M. (fourth day). Sharp pain in epigastric region (after four hours and a half, third day).


Umbilicus. Shooting pain through left umbilical region, from before backward (after nine hours). During the evening, some pain in umbilical region (third day). Quite a sharp pain about umbilicus, on left side (seventh day). Stitches through the right side in region of liver; seem to be mostly in the muscles (second day). General Abdomen. Fullness of abdomen (after seven hours).

Much flatus, in the evening (third day). Flatus during the day (eleventh day). Wind in the bowels passed up and down, not marked (sixth day). Pass a great deal of wind from the bowels on moving (third day). Flatus, with much rumbling in abdomen (seventh day).

Rumbling and much flatus (fourth day). Rumbling in the abdomen, with crampy pain and flatus (after three hours, third day).

Rumbling in small intestines (after one hour). Awoke at 7 A.M., with dull, rumbling, and colic like pains in the abdomen (sixth day). Rumbling pain in the abdomen (after four hours, fifth day).

Awoke with pain in the abdomen, and strong erections (third day).

Crawling stinging pains in abdomen (fourth day). Some pain in abdomen and neck of bladder (sixth day). Pain in bowels, lasting all the forenoon, with very little headache; pain in bowels less than usual (after third dose, third day). Hypogastrium and Iliac Regions. Occasionally, all day long in hypogastrium, a sensation of giving way (second day). A slight vacant and sore feeling in hypogastric region (first day). Slight colicky pains worse (third day). Severe pain in the left inguinal region, on walking, and aggravated by going upstairs (after eight hours). At night (11 o’clock), an aching sharp pain in right iliac region above the ovary, sore on pressure (eighth day).

Rectum and Anus,

Sharp pain shooting around the anus, at 9 P.M. (thirty-ninth day). Stinging and itching at the anus during and after defection (second day).


Diarrhoea. Diarrhoeic stool, with burning and smarting at the anus (fifth day). Four thin stools, with great prostration. Stool twice before 9 A.M., like gruel, slightly yellow or yellowish- gray (third day). Stool rather copious, oily, yellowish (after one hours); repeated (after two hours); again (after two hours and three- quarters). Stools loose, light-colored, with cutting and smarting at the anus, during and after defecating (second day). Stools light-colored, and passed with much burning and smarting in the anus, continuing an hour afterwards (eighth day).

Soft, light-colored stool, passed with much straining (sixth day); soft stool, with tenesmus (tenth day). Scanty, soft stool, with burning at the anus, at 3 P.M. (second day). Small, ineffectual, soft stool, followed by drawing up of the anus, and accompanied by some tenesmus (third day). Stools shoot away in soft plugs, followed by much flatus; bowels move very easily (after eight hours, second day). For some time had been quite constipated, but now have a passage every day (seventh day).

Bowels continue regular, passing easily at night and morning; passage very quick, as if greased, followed by much wind; stools have a strange odor, but not disagreeable, rather a sweetish smell, as of boiling sap (seventh day). Constipation. Bowels constipated; only one difficult passage to-day (eight day); very much constipated in evening, no movement of bowels; pressing-down sensation in rectum, with desire for stool, but could pass nothing (ninth day); bowels regular (eleventh day).

Urinary organs

Bladder and Urethra. In the evening, a sharp pain in region of bladder, worse on the right side, lasting only a few seconds (fourth day). Some pain in region of bladder and in abdomen generally (fourth day). Burning during urinating, and after (second day). A sensation of jerking drawing in the urethra (after second dose, thirteenth day). Slight pain after micturition (twelfth day). Micturition. During the morning more frequent micturition than usual (fifth and sixth days). In passing urine it kept dribbling after I got through (second day).

Urine. Urine profuse (second day); urine had become scanty (sixth day); dark-yellow, with strong odor (eighth day). Increased flow of pale urine (second day). Increased flow of urine (fifth, eleventh, and thirteenth days). Urine increased, light-colored; specific gravity, 10.23 (ninth day). Before the proving, it had given acid reaction; specific gravity, 1020. Urine profuse; color normal; very hot when passed, accompanied with burning pain in urethra (fifth day); urine passed with burning, scalding pain (seventh day). Urine increased, and of a light-amber color (eighth day); increased and of a light color, at & P.M. (ninth day); still pale and increased (twelfth day). Urine yellow in the;morning, and of an increased quantity during the day (twelfth day). Urine continued yellow for some time after discontinuance of drug. Urine dark-red, in the evening (third day). Urine dark, specific gravity, 1030; indications of sugar; the test was good with the copper solution, also by fermentation test (fourth day); very highly colored (fifth day). (* As I have not been able to get such testimony from any other prover, I hold his evidence sub judice.-S.A. JONES. *) Urine dark, high-colored; specific gravity 1025 to 1028;; quantity about normal; urination followed by burning (fifth day). Urine highly colored (tenth day). Urine of a milky olive hue (thirteenth day). Urine red (after two hours).

Urine light-colored and profuse, burning in the urethra, during and after urinating; urethra feels as if burnt (second day).

Urine normal in color, but much less in the previous twenty- four hours has a heavy deposit of urates (third day). Urine rather scanty, of a dark-yellow color (tenth day); yellow and profuse (twelfth day); very profuse (thirteenth and fourteenth days).

About the author

TF Allen

TF Allen

Dr. Timothy Field Allen, M.D. ( 1837 - 1902)
Born in 1837in Westminster, Vermont. . He was an orthodox doctor who converted to homeopathy
Dr. Allen compiled the Encyclopedia of Pure Materia Medica over the course of 10 years.
In 1881 Allen published A Critical Revision of the Encyclopedia of Pure Materia Medica.

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